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Thermo Fisher Scientific mGluR5 Polyclonal Antibody
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Thermo Fisher Scientific mGluR5 Polyclonal Antibody

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mGluR5 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, IP 등에 사용 가능. 인간, 토끼, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 0.5 mg/mL 농도의 액상 형태로 제공. 단기 4°C, 장기 -20°C 보관 권장.

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Thermo Fisher Scientific 500-2874 mGluR5 Polyclonal Antibody 100 ug pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific mGluR5 Polyclonal Antibody

Thermo Fisher Scientific mGluR5 Polyclonal Antibody

Applications and Tested Dilution

Application Tested Dilution
Western Blot (WB) 0.1–1 µg/mL
Immunohistochemistry (Paraffin) (IHC (P)) 2–10 µg/mL
Immunoprecipitation (IP) 2–5 µg/mL

Product Specifications

Specification Description
Species Reactivity Human, Rabbit, Rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Synthetic peptide derived from C-terminus of human Glutamate receptor
Conjugate Unconjugated
Form Liquid
Concentration 0.5 mg/mL
Purification Antigen affinity chromatography
Storage Buffer PBS with proprietary stabilizer
Contains 0.01% sodium azide
Storage Conditions Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Positive control: Brain tissue
  • Cellular location: Cytoplasmic, membrane

Target Information

GRK1 is a member of the G protein-coupled receptor kinase (GRK) subfamily within the Serine/Threonine kinase family. It phosphorylates rhodopsin to initiate deactivation. Phosphorylation promotes arrestin binding, terminating receptor signaling. GRK1 is farnesylated for membrane association and inhibited by recoverin, a calcium-binding protein.
Diseases associated with GRK1 dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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