Thermo Fisher Scientific DYRK1B Polyclonal Antibody
Rabbit polyclonal antibody recognizing human DYRK1B for WB and IP applications. High specificity with affinity-purified formulation. Supplied as liquid, unconjugated form. Suitable for research use in cell signaling and protein expression studies.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the carboxyl terminus of human DYRK1B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 39 µg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981743 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
DYRK1B is a member of the DYRK family of protein kinases and is proposed to be involved in nuclear functions. Integrins are heterodimers comprised of alpha and beta subunits that are noncovalently associated transmembrane glycoprotein receptors. Integrins mediate cell-matrix or cell-cell adhesion and transduce signals that regulate gene expression and cell growth. DYRK1B encodes the integrin beta 4 subunit, a receptor for laminins. Mutations in DYRK1B are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for DYRK1B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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