Thermo Fisher Scientific ARHGAP22 Polyclonal Antibody
ARHGAP22 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 및 면역세포화학(ICC/IF)에 적합. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도. 인간 및 마우스 시료 반응성. 연구용 한정.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ARHGAP22 (Accession Q7Z5H3), corresponding to amino acid residues L564–R614 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853577 |
Product Specific Information
Antibody detects endogenous levels of total ARHGAP22.
Target Information
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form.
ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698 amino acid protein localized in the cytoplasm. It contains one Rho-GAP domain and one PH domain.
ARHGAP22 functions as a GTPase-activating protein for Rac1, converting it to an inactive GDP-bound state. Through its interaction with ZNF161 (VEZF1), it may be involved in transcription regulation. Multiple isoforms exist due to alternative splicing events.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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