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Thermo Fisher Scientific PD-L1 Monoclonal Antibody (UMAB228), UltraMAB
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Thermo Fisher Scientific PD-L1 Monoclonal Antibody (UMAB228), UltraMAB

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Human PD-L1 단백질(aa 19-290)을 인식하는 Mouse IgG1 단클론 항체로, Western Blot 및 IHC(Paraffin)에 적합. 비결합형 액상 형태로 제공되며, 고순도의 친화 크로마토그래피 정제 제품. 암 연구 및 면역조절 관련 연구용으로 사용 가능.

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Thermo Fisher Scientific UM800120 PD-L1 Monoclonal Antibody (UMAB228), UltraMAB 100 ul pk판매 단위 pk
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Thermo Fisher Scientific UM870120 PD-L1 Monoclonal Antibody (UMAB228), UltraMAB 30 ul pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific PD-L1 Monoclonal Antibody (UMAB228), UltraMAB

Applications

Application Tested Dilution Publications
Western Blot (WB) 1:500 -
Immunohistochemistry (Paraffin) (IHC (P)) 1:300 -
Miscellaneous PubMed (Misc) - View 1 publication

Product Specifications

항목 내용
Species Reactivity Human
Published Species Not Applicable
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone UMAB228
Immunogen Human recombinant protein fragment corresponding to amino acids 19–290 of human CD274 (PD-L1) produced in E. coli
Conjugate Unconjugated
Form Liquid
Concentration 0.5–1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

Programmed death receptor ligand 1 (PD-L1, also called B7-H1) is a member of the B7 family. PD-L1 binds to its receptor, PD-1, which negatively regulates T-cell receptor (TCR) signaling. Upon ligation, PD-L1 decreases TCR-mediated proliferation and cytokine production. PD-L1 expression is abundant in many murine and human cancers and can be upregulated by IFN-γ stimulation, suggesting its role in tumor immune evasion.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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