Thermo Fisher Scientific BMAL1 Polyclonal Antibody
BMAL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot, IHC, ICC 등 다양한 응용에 사용 가능하며, 인간, 생쥐, 햄스터, 랫트 반응성을 보입니다. 항원 친화 크로마토그래피로 정제된 액상 항체로, 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 2 publications |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 2 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Hamster, Human, Mouse, Rat |
| Published Species | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: CD(582)MIDNDQGSSSPS(594) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2059614 |
Product Specific Information
PA1-523 detects BMAL1/aryl hydrocarbon nuclear translocator 3 (ARNT3) from hamster and mouse tissues as well as recombinant human BMAL1.
It has been successfully used in Western blot procedures. By Western blot, this antibody detects a 110 kDa protein corresponding to a hamster GST-BMAL1 fusion construct overexpressed in E. coli.
A non-specific band is observed in U87-MG cell lysates at ~105 kDa and in NIH-3T3 cell lysates at ~135 kDa.
The immunizing peptide corresponds to amino acid residues 582–594 from mouse BMAL1. This sequence is completely conserved between mouse, rat, guinea pig, and human BMAL1.
PA1-523 immunizing peptide (Cat. # PEP-075) is available for use in neutralization and control experiments.
Target Information
The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK.
This complex binds an E-box upstream of the PER1 gene, activating this gene and other circadian rhythm-associated genes.
Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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