Thermo Fisher Scientific SLC28A2 Polyclonal Antibody
Human SLC28A2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 실험에 최적화됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 완충액에 보관. 인간 CNT2 단백질 연구 및 뉴클레오시드 수송 관련 연구에 적합.
- 카탈로그번호
- PA563151
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SLC28A2. Recombinant protein control fragment (Product # RP-103224) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2647437 |
Product Specific Information
Immunogen sequence:
GAEADCVSFP NTSFTNRTYE TYMCCRGLFQ STSLNGTNPP SFSGPWEDKE FSAMALTNCC GFYNNTVCA
Highest antigen sequence identity to the following orthologs:
- Mouse: 72%
- Rat: 74%
Target Information
The concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2, and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of anticancer and antiviral nucleoside analogs, as the CNT proteins modulate their entry into target tissues. Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K⁺ channels.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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