Thermo Fisher Scientific SLC28A2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SLC28A2. Recombinant protein control fragment (Product #RP-103224). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SLC28A2,uniProtId:O43868-1,ncbiNodeId:9606,antigenRange:590-658,antigenLength:658,antigenImageFileName:PA5-63151_SLC28A2_O43868-1_Rabbit.svg,antigenImageFileNamePDP:PA5-63151_SLC28A2_O43868-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647437

Product Specific Information

Immunogen sequence: GAEADCVSFP NTSFTNRTYE TYMCCRGLFQ STSLNGTNPP SFSGPWEDKE FSAMALTNCC GFYNNTVCA

Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 74%.

Target Information

The concentrative nucleoside transporter (CNT) family comprises three members: CNT1, CNT2 and CNT3. CNT2 participates in the absorption and disposition of endogenous nucleosides and mediates the first step of nucleotide biosynthesis. CNT2 levels are highly dependent on insulin (but not glucose) concentration, and the protein is under the control of the Adenosine 1 receptor. CNT family members are imperative in the response of cells to a variety of anticancer and antiviral nucleoside analogs, as the CNT proteins modulate their entry into target tissues. Increasing evidence also suggests that CNT2 may have a role in energy metabolism because activation of CNT2 relies on the opening of ATP-sensitive K+ channels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.