Thermo Fisher Scientific MRPL28 Polyclonal Antibody
Human MRPL28 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS buffer와 40% glycerol에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MRPL28. Recombinant protein control fragment (Product # RP-103222) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644138 |
Product Specific Information
Immunogen sequence:
PVWLWKRLQL REGICSRLPG HYLRSLEEER TPTPVHYRPH GAKFKINPKN GQRERVEDVP IPIYFPPESQ RGLWGGEGWI LGQIYANND
Antigen sequence identity:
- Mouse: 81%
- Rat: 80%
Target Information
MRP-L28 (39S ribosomal protein L28, melanoma-associated antigen recognized by T lymphocytes) is a mitochondrial protein belonging to the ribosomal protein L28P family.
It may serve as a therapeutic reagent for HLA-A24 (A24) patients, as it is recognized by tumor-infiltrating lymphocyte (TIL) 1290 targeting the A24 serotype.
HLA-A24 is a serotype identifying the HLA-A24 gene products, common in Austronesia and populations such as Papua New Guineans, indigenous Taiwanese, Yupik, and Greenland Eskimos.
MRP-L28 is expressed in normal tissues including spleen, testis, thymus, liver, kidney, brain, adrenal, lung, and retina.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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