Thermo Fisher Scientific DEPDC5 Polyclonal Antibody
Human DEPDC5 단백질을 인식하는 Rabbit Polyclonal 항체. ICC/IF에 사용 가능하며, 고순도의 항원 친화 크로마토그래피로 정제됨. PBS 버퍼(40% glycerol) 용액 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DEPDC5. Recombinant protein control fragment (Product # RP-95351) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640530 |
Product Specific Information
Immunogen sequence:
YDAQVFRLPG PSRAQCLTTC RSVRERESHS RKSASSCDVS SSPSLPSRTL PTEEVRSQAS DDSSLGKSAN ILMIPHPHLH QYEVSSS
Highest antigen sequence identity to the following orthologs:
- Mouse: 92%
- Rat: 91%
Target Information
This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways.
The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing nutrient availability.
The encoded protein is a component of the GATOR1 complex, which inhibits the amino acid-sensing branch of the mTORC1 pathway.
Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci.
A single nucleotide polymorphism in an intron of this gene has been linked to increased hepatocellular carcinoma risk in individuals with chronic hepatitis C virus infection.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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