Thermo Fisher Scientific Calpain 11 Polyclonal Antibody
인간 Calpain 11 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, IHC, ICC/IF 등 다양한 응용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CAPN11 (Accession Q9UMQ6), corresponding to amino acid residues A405–H455 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850913 |
Product Specific Information
Antibody detects endogenous levels of total CAPN11.
Target Information
The calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that function as nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large catalytic subunits and a common small regulatory subunit. The CAPN1 gene encodes the large subunit of the ubiquitous enzyme calpain 1. Several transcript variants encoding two different isoforms have been identified. Diseases associated with CAPN1 include Spastic Paraplegia 76 (Autosomal Recessive) and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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