Thermo Fisher Scientific Phospho-RelA (Ser468) Polyclonal Antibody
NF-κB p65(Ser468) 인산화 형태를 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응. IHC 및 Paraffin IHC에 사용 가능하며 항원 친화 크로마토그래피로 정제됨. 4°C 보관, 연구용으로만 사용.
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Thermo Fisher Scientific Phospho-RelA (Ser468) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Human v-rel reticuloendotheliosis viral oncogene homolog A surrounding serine 468 when serine 468 is phosphorylated |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, Rat, Bovine, Dog, Horse, Guinea pig, Pig, Panda, Orangutan, Monkey, Gorilla, and Chimpanzee
Target Information
Nuclear factor kB p65 (NF-κB p65) is encoded by the RELA gene located on chromosome 11 in humans.
NF-κB p65, also known as RelA, belongs to the Rel family of proteins and forms a heterodimer with p50 or p52 subunits.
Upon TNFα stimulation, phosphorylation of IKK leads to IκB phosphorylation and subsequent proteasomal degradation, allowing NF-κB activation.
It plays a key role in transcription of the immunoglobulin κ gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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