Thermo Fisher Scientific alpha Adducin Polyclonal Antibody
Thermo Fisher Scientific의 alpha Adducin Polyclonal Antibody는 인간, 마우스, 랫트에 반응하며 Western blot 및 IHC(P) 분석에 적합합니다. 합성 펩타이드 유래 항원으로 제작된 고품질 토끼 IgG 항체로, 액상형이며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ADD1 (Accession P35611), corresponding to amino acid residues G700–S737 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2851839 |
Product Specific Information
Antibody detects endogenous levels of total ADD1.
Target Information
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein composed of related subunits produced from distinct genes but sharing a similar structure.
Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region.
Alpha- and gamma-adducins are ubiquitously expressed, while beta-adducin is highly expressed in brain and hematopoietic tissues.
Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C.
Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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