Thermo Fisher Scientific SULT1A1 Polyclonal Antibody
SULT1A1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(Paraffin) 분석에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SULT1A1 (Accession P50225), corresponding to amino acid residues G65–P115 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851840 |
Product Specific Information
This antibody detects endogenous levels of total SULT1A1.
Target Information
The soluble sulfotransferases contribute to the elimination of xenobiotics, activation of procarcinogens, and regulation of hormones by catalyzing sulfate conjugation.
Members of the SULT1, SULT2, and SULT3 groups show substrate selectivity.
SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295-amino acid cytoplasmic protein belonging to the sulfotransferase family.
It functions as a homodimer expressed in brain, liver, skin, and lung tissue, catalyzing the sulfate conjugation of catecholamines, phenolic drugs, and neurotransmitters.
Through this activity, SULT1A1 plays a role in the elimination of various compounds and may also contribute to the activation of carcinogenic N-hydroxyarylamines, indicating potential involvement in carcinogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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