Thermo Fisher Scientific MFNG Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MFNG. Recombinant protein control fragment (Product #RP-101136). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MFNG,uniProtId:O00587-1,ncbiNodeId:9606,antigenRange:62-133,antigenLength:321,antigenImageFileName:PA5-61842_MFNG_O00587-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61842_MFNG_O00587-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643920

Product Specific Information

Immunogen sequence: TTRAFHRLRL ELLLDTWVSR TREQTFVFTD SPDKGLQERL GSHLVVTNCS AEHSHPALSC KMAAEFDTFL AS

Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 88%.

Target Information

This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.