Thermo Fisher Scientific MYO3A Polyclonal Antibody
인간 MYO3A 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200–1:500 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 완충액에 보존. 청각 관련 MYO3A 단백질 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MYO3A. Recombinant protein control fragment (Product #RP-101134) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644370 |
Product Specific Information
Immunogen sequence:
IIIQSAARGH LVRKQRKEIV DMKNTAVTTI QTSDQEFDYK KNFENTRESF VKKQAENAIS ANERFISAPN NKGSVSVVKT STFKPEEETT NAV
- Highest antigen sequence identity to orthologs:
- Mouse: 57%
- Rat: 55%
Target Information
MYO3A (MYO3 alpha) serine/threonine kinase belongs to the myosin superfamily, categorized into conventional (class II) and unconventional myosins (classes I and III–XV) based on their variable C-terminal cargo-binding domains.
Class III myosins, such as MYO3A, have a kinase domain N-terminal to the conserved motor domains and are expressed in photoreceptors.
MYO3A plays an important role in human hearing, and mutations in MYO3A are associated with nonsyndromic progressive hearing loss.
It is highly expressed in the retina and cochlea.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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