Thermo Fisher Scientific MYO3A Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human MYO3A. Recombinant protein control fragment (Product #RP-101134). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MYO3A,uniProtId:Q8NEV4-1,ncbiNodeId:9606,antigenRange:1087-1179,antigenLength:1616,antigenImageFileName:PA5-61844_MYO3A_Q8NEV4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61844_MYO3A_Q8NEV4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644370

Product Specific Information

Immunogen sequence: IIIQSAARGH LVRKQRKEIV DMKNTAVTTI QTSDQEFDYK KNFENTRESF VKKQAENAIS ANERFISAPN NKGSVSVVKT STFKPEEETT NAV

Highest antigen sequence identity to the following orthologs: Mouse - 57%, Rat - 55%.

Target Information

MYO3A (MYO3 alpha) serine/threonine kinase belongs to the myosin superfamily where they are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3A, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. MYO3A plays an important role in hearing in humans and mutations in the MYO3A have been shown to cause nonsyndromic progressive hearing loss. MYO3A is highly expressed in retina and cochlea.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.