Merck Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6

Anti-Na+/K+ ATPase α-1 Antibody, clone C464.6

clone C464.6, Upstate®, from mouse

ATPase, Na+/K+ transporting, alpha 3 polypeptide, Na(+)/K(+) ATPase alpha(III) subunit, Na(+)/K(+) ATPase alpha-3 subunit, Na+/K+ -ATPase alpha 3 subunit, Na+/K+ ATPase 3, Sodium pump subunit alpha-3, dystonia 12, sodium pump 3, sodium-potassium-ATPase,

Quality Level

100

생물학적 소스

mouse

항체 형태

purified immunoglobulin

antibody product type

primary antibodies

클론

C464.6, monoclonal

species reactivity

rat, sheep, human, pig, monkey, Xenopus, mouse, rabbit, canine

포장

antibody small pack of 25 μg

manufacturer/tradename

Upstate®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

동형

IgG1κ

NCBI 수납 번호

NM_001001586

UniProt 수납 번호

P05023

배송 상태

dry ice

Gene Information

human ... ATP1A3(478)

Na+/K+-ATPase (also known as the Na+/K+ pump or sodium-potassium pump) is an enzyme located in the plasma membrane (specifically an electrogenic transmembrane ATPase). It is found in the plasma membrane of virtually every human cell and is common to all cellular life. It helps maintain cell potential and regulate cellular volume.
In order to maintain the cell potential, cells must keep a low concentration of sodium ions and high levels of potassium ions within the cell (intracellular). Outside cells (extracellular), there are high concentrations of sodium and low concentrations of potassium, so diffusion occurs through ion channels in the plasma membrane. In order to keep the appropriate concentrations, the sodium-potassium pump pumps sodium out and potassium in through active transport.