Merck Anti-CTCF Antibody

Anti-CTCF Antibody

serum, Upstate®

11 zinc finger transcriptional repressor, 11-zinc finger protein, CCCTC-binding factor, CCCTC-binding factor (zinc finger protein), CTCFL paralog, transcriptional repressor CTCF

생물학적 소스

rabbit

Quality Level

100

항체 형태

serum

antibody product type

primary antibodies

클론

polyclonal

species reactivity

human, mouse, primate, rat, canine

포장

antibody small pack of 25 μL

manufacturer/tradename

Upstate®

technique(s)

ChIP: suitable (ChIP-seq)
western blot: suitable

NCBI 수납 번호

NM_006565.2

UniProt 수납 번호

P49711

배송 상태

ambient

Gene Information

human ... CTCF(10664)

CTCF is a ubiquitous 11 zinc finger (ZF) protein with highly versatile functions. A transcriptional repressor, CTCF, binds to promoters of vertebrate c-myc gene. It also binds to the PLK and PIM1 promoters. CTCF may prevent the access of transcriptional activators to enhancers. CTCF also acts as a transcriptional activator of APP. It is involved in different aspects of gene regulation including promoter activation or repression, hormone-responsive gene silencing, methylation-dependent chromatin insulation, and genomic imprinting. CTCF may also act as tumor suppressor. CTCF organizes epigenetically controlled chromatin insulators that regulate imprinted genes in soma.