Merck Kallikrein-3 human

Kallikrein-3 human

제품 개요

Recombinant human Kallikrein-3 (Prostate-specific antigen, PSA)은 인간 세포에서 발현된 단백질로, 높은 순도(≥95%, SDS-PAGE)를 가진 재조합 단백질입니다. 전립선 특이 항원으로 알려진 이 단백질은 전립선암 연구 및 진단 관련 연구에 널리 사용됩니다.

주요 특징

• Recombinant human protein (expressed in human cells)
• Purity ≥95% (SDS-PAGE)
• Lyophilized form
• Molecular weight: 35 kDa
• Supplied in 20 μg package

제품 정보

유전자 정보

• Gene: KLK3 (354)
• Synonyms: APS, Kallikrein-3, P-30 antigen, Hk3, PSA, KLK2A1

제품 설명

Prostate-specific antigen (PSA), also known as Gamma-seminoprotein, Kallikrein-3, or KLK3, is a secreted glycoprotein belonging to the peptidase S1 family and Kallikrein subfamily. It is produced almost exclusively by the prostate gland and functions to liquefy the seminal coagulum, facilitating sperm motility. KLK3 is also believed to play a role in dissolving cervical mucus to allow sperm entry.
Human KLK3 and KLK2 are closely related products of the kallikrein gene family, both secreted by the prostate. These proteins are important biomarkers in prostate cancer diagnosis. Understanding genetic variations in KLK3 is critical for studying its role in prostate tumorigenesis.