Merck Monoclonal Anti-Vinculin antibody produced in mouse

Monoclonal Anti-Vinculin antibody produced in mouse

clone hVIN-1, ascites fluid

Quality Level

200

생물학적 소스

mouse

결합

unconjugated

항체 형태

ascites fluid

antibody product type

primary antibodies

클론

hVIN-1, monoclonal

분자량

antigen 116 kDa

포함

15 mM sodium azide

species reactivity

bovine, canine, mouse, rat, turkey, human, chicken, frog

향상된 검증

independent
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technique(s)

immunohistochemistry (frozen sections): suitable
indirect immunofluorescence: 1:400 using cultured human fibroblasts
western blot: 1:200 using extract of human fibroblasts

동형

IgG1

UniProt 수납 번호

P18206

application(s)

research pathology

배송 상태

dry ice

저장 온도

−20°C

Gene Information

human ... VCL(7414)
mouse ... Vcl(22330)
rat ... Vcl(305679)

Monoclonal Anti-Vinculin (mouse IgG1 isotype) is derived from the hVIN-1 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from immunized BALB/c mice. Vinculin is localized in the fascia adherens of the intercalated disk (cardiac muscle), myotendinous junctions (skeletal muscle), neuromuscular junctions and the membrane-associated dense bodies of smooth muscle. In many cell types undergoing viral transformation, vinculin becomes redistributed to rosettes or podosomes.