Merck Anti-β-Tubulin III antibody produced in rabbit

Anti-β-Tubulin III antibody produced in rabbit

제품 개요

• Affinity isolated antibody
• Buffered aqueous solution
• Unconjugated
• Primary antibody (polyclonal)

생물학적 소스

rabbit

스펙 정보

적용 기술

• Immunoprecipitation (IP): 10 μg using RIPA extract (250 μg) of cultured rat PC12 cells
• Indirect immunofluorescence: 10–20 μg/mL using rat PC12 cells
• Western blot: 0.2–0.4 μg/mL using whole extracts of mouse brain or cultured human neuroblastoma SH-SY5Y cells

Gene Information

제품 설명

Tubulin β 3 class III (TUBB3), also known as β-Tubulin III, is encoded by the gene mapped to human chromosome 16q24.3. TUBB3 protein expression is restricted to neurons.
α/β-Tubulin, an integral component of microtubules, is present in almost all eukaryotic cells.
α/β-Tubulin occurs mostly as soluble (approx. 100–110 kDa) heterodimeric sets of α- and β-tubulin isotypes or as polymers in assembled microtubules.
β-Tubulin III (also designated β-4 chain) is found in the brain and dorsal root ganglia and appears to be localized to neurons of the central and peripheral nervous system.
β-Tubulin III is also found in Sertoli cells of the testis, spermatozoa tails, certain lung cells, and apparently some breast stromal cells.

제품 이미지

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