Merck MISSION Lenti microRNA Inhibitor, Mouse

MISSION® Lenti microRNA Inhibitor, Mouse

mmu-miR-5107-3p

Tough Decoy (TuD) Design

제품 개요

Individual lenti microRNA inhibitors are designed using a proprietary algorithm developed in collaboration with Dr. Hideo Iba (University of Tokyo), based on the work of Haraguchi, T. et al.
This algorithm utilizes the Tough Decoy (TuD) design for potent inhibition of target miRNA.

miRNA are known to regulate gene expression through translational repression, mRNA cleavage, and deadenylation.
The lentiviral microRNA inhibitors are cloned into the TRC2-pLKO-puro vector, which includes the Woodchuck Hepatitis Post-Transcriptional Regulatory Element (WPRE) for enhanced transgene expression.
This vector also carries a puromycin resistance gene for cell selection.

주요 특징

• 강력한 miRNA 억제 효과 (TuD 구조 적용)
• Lentiviral 전달 방식으로 다양한 세포 유형에 효율적 적용
• 반복적인 형질감염 없이 장기적 억제 가능
• Puromycin 저항성 유전자 및 WPRE 포함으로 발현 효율 향상

제품 스펙

참고 정보

Lentiviral delivery format allows for efficient delivery of the inhibitor into a wide variety of cell types.
Enables long-term inhibition without repeat transfection.

제품 이미지

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