Merck CCL6 from mouse

CCL6 from mouse

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

MRP-1, C10, CCL6, SCYA6

생물학적 소스

mouse

재조합

expressed in HEK 293 cells

태그

6-His tagged (C-terminus)

assay

≥95% (SDS-PAGE)

form

lyophilized powder

분자량

calculated mol wt 11.4 kDa (The predicted N-terminus is Gly22.)
observed mol wt 14 kDa by SDS-PAGE (reducing)

포장

pkg of 10 μg

불순물

<1 EU/μg endotoxin (LAL test)

UniProt 수납 번호

P27784

배송 상태

wet ice

저장 온도

−20°C

Gene Information

mouse ... CCL6(20305)

Chemokine (C-C motif) ligand 6 (CCL6), a member of the CC chemokine family, was initially identified as a transcript that is induced in bone marrow cells upon stimulation with GM-CSF. CCL6 has only been identified in rodents. A human homologue for mouse CCL6 has not been identified. The mCCL6 cDNA encodes a 116 amino acid residue precursor protein with a hydrophobic signal peptide that is cleaved to yield a 95 amino acid residue mature protein. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, where it is strongly induced upon GM-CSF stimulation. Mouse CCL6 expression was also shown to be strongly induced by interleukin-4 (IL-4) in mouse macrophages and by cytokine IL-13 in mouse lung. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.