Thermo Fisher Scientific CD153 Polyclonal Antibody
CD153 단백질을 표적하는 Rabbit Polyclonal 항체로, Western Blot 및 Immunocytochemistry에 사용 가능. 인간 및 생쥐 반응성. 고순도 친화 크로마토그래피 정제. PBS/glycerol buffer에 보관하며 -20°C에서 안정적. 연구용으로만 사용.
- 카탈로그번호
- PA5101104
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TNFSF8 (Accession P32971), corresponding to amino acid residues C49–W99 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850548 |
Product Specific Information
Antibody detects endogenous levels of total CD153.
Target Information
The ligand for CD30 is CD30L (CD153). The binding of CD30 to CD30L mediates pleiotropic effects including cell proliferation, activation, differentiation, and apoptotic cell death. CD30 has a critical role in the pathophysiology of Hodgkin’s disease and other CD30+ lymphomas. CD30 acts as a costimulatory molecule in thymic negative selection. In addition to its expression on Hodgkin’s and Reed-Sternberg cells, CD30 is also found in some non-Hodgkin’s lymphomas (including Burkitt’s lymphomas), virus-infected T and B cells, and on normal T and B cells after activation. In T cells, CD30 expression is present on a subset of T cells that produce Th2-type cytokines and on CD4+/CD8+ thymocytes that coexpress CD45RO and the IL4 receptor.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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