Thermo Fisher Scientific Human PDGF-B Recombinant Protein
Recombinant human PDGF-B 단백질로, E. coli에서 발현된 고순도(>95%) His-tag 단백질입니다. 다양한 면역학적 분석에서 양성 대조군으로 사용 가능하며, 발달 및 세포 성장 관련 연구에 적합합니다. -20°C에서 보관하며 동결/해동을 피해야 합니다.
- 카탈로그번호
- RP75693
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Amino acids Ser82–Thr190 containing an N-terminal His-tag |
| Tag | His-tag |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Purified |
| Storage Buffer | 25 mM sodium acetate, pH 4.8, with 1 mM EDTA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
RP-75693 contains purified recombinant human PDGF-B protein with an N-terminal hexahistidine tag.
RP-75693 may be used as a positive control in many immunological assays.
Target Information
This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize or heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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