Thermo Fisher Scientific Human PAPPA Recombinant Protein
인간 유래 PAPP-A 재조합 단백질로, N-말단 His-tag을 포함하며 순도 95% 이상입니다. 다양한 면역학적 분석에서 양성 대조군으로 사용 가능하며, E. coli 발현 시스템으로 생산되었습니다. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Human PAPPA Recombinant Protein
Applications
- Western Blot (WB): Assay-dependent
- Control (Ctrl): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | E. coli |
| Amino Acid Sequence | Amino acids Arg81–Asp271 containing an N-terminal His-tag |
| Tag | His-tag |
| Class | Recombinant |
| Type | Protein |
| Purity | >95%, by SDS-PAGE under reducing conditions |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 3.0 mg/mL |
| Purification | Purified |
| Storage Buffer | 4M urea / 20mM Tris HCl, pH 8, with 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Product Specific Information
This product contains purified recombinant human Pregnancy Associated Plasma Protein-1 (PAPP-A) with an N-terminal hexahistidine tag.
It may be used as a positive control in various immunological assays.
Target Information
Pregnancy-associated plasma protein-A (PAPP-A, Insulin-like growth factor binding protein-4 protease, PAPP-A-proMBP complex) is a large heterotetrameric glycoprotein (~500 kDa) first discovered in serum from pregnant women.
The heterotetramer consists of two PAPP-A subunits and two proMBP subunits.
Low maternal serum levels of PAPP-A during first trimester screening are used as a marker for Down’s syndrome (trisomy 21).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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