Thermo Fisher Scientific CDK5 Monoclonal Antibody (DC34)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500

View 11 publications 11 publications

Immunohistochemistry (IHC)

-

- -

Immunohistochemistry (Paraffin) (IHC (P))

-

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

5 µg/mL

View 3 publications 3 publications

Immunoprecipitation (IP)

Assay-Dependent

View 2 publications 2 publications

Product Specifications

Published species

Human, Mouse, Non-human primate, Rat

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

DC34

Immunogen

Recombinant cdk5 protein.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Storage conditions

4° C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2536380

Product Specific Information

Suggested positive controls include HT29, MAD109, PC12 cells and brain tissue.

Target Information

CDK5 is a member of the Cyclin-Dependent Kinase family that is most abundant in the mammalian brain. Active form of CDK5, which has also been called neuronal cdc2-like kinase, is a heterodimer of CDK5 and a 25 kDa protein which is derived proteolytically from a 35 kDa brain and neuron-specific protein and is essential for the kinase activity of CDK5. CDK5 has emerged as a crucial regulator of neuronal migration in the developing central nervous system. CDK5 phosphorylates a diverse list of substrates, implicating it in the regulation of a range of cellular processes - from adhesion and motility, to synaptic plasticity and drug addiction.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.