Thermo Fisher Scientific NKG2D Monoclonal Antibody (1D11), APC
인간 NKG2D (CD314) 항원을 인식하는 Mouse IgG1 단일클론 항체로 APC 형광체가 결합되어 있습니다. Flow Cytometry에 적합하며 NK, γδ T, CD8+ T 세포의 활성 수용체 분석에 활용됩니다. 액상 형태로 제공되며 4°C 암소 보관이 필요합니다.
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Thermo Fisher Scientific NKG2D Monoclonal Antibody (1D11), APC
Applications
- Flow Cytometry (Flow)
Tested Dilution: 10 µL / 1×10⁶ cells
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1D11 |
| Immunogen | NKL cell line |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2534505 |
Additional Formats
- Unconjugated (Cat. MA5-46196)
- FITC (Cat. A15760)
- Custom conjugation available upon request
Product Specific Information
This antibody recognizes an extracellular epitope of CD314 / NKG2D, a 42 kDa C-type lectin-like activating receptor expressed by NK cells, gamma/delta T cells, and CD8+ T cells.
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. NK cells regulate specific humoral and cell-mediated immunity and preferentially express several calcium-dependent (C-type) lectins, which are implicated in NK cell function regulation.
The NKG2 gene encodes a member of the NKG2 family, characterized by a type II membrane orientation (extracellular C terminus) and a C-type lectin domain. The NKG2 gene family resides within the NK complex, a region containing several C-type lectin genes expressed in NK cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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