Thermo Fisher Scientific PFKP Polyclonal Antibody
Thermo Fisher Scientific의 PFKP Polyclonal Antibody는 인간 PFKP 단백질에 특이적인 토끼 IgG 폴리클로날 항체입니다. Western blot 및 면역세포화학(ICC/IF)에 적합하며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Thermo Fisher Scientific PFKP Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PFKP. Recombinant protein control fragment (Product #RP-105043). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2791447 |
Product Specific Information
Immunogen sequence:
MECVQMTQDV QKAMDERRFQ DAVRLRGRSF AGNLNTYKRL AIKLPDDQIP KTNCNVAVIN V
Target Information
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the γ phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.
With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including:
- Cyclic nucleotide-regulated protein kinase (PKA & PKG) family
- Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family
- Related to PKA and PKC (RAC/Akt) protein kinase family
- Kinases that phosphorylate G protein-coupled receptors (ARK) family
- Kinases that phosphorylate ribosomal protein S6 (RSK) family
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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