Thermo Fisher Scientific TL1A Polyclonal Antibody
TL1A 단백질을 표적하는 Rabbit Polyclonal Antibody로 Western blot에 적합. Human에 반응하며 Mouse, Pig 등에서도 예측 반응성 있음. 항원 친화 크로마토그래피로 정제된 액상 시약으로 4°C 또는 -20°C에 보관. 연구용 전용 제품.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 187–251 of Human TL1A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546301 |
Product Specific Information
- Recommended positive controls: A431, HeLa, HepG2
- Predicted reactivity: Mouse (100%), Pig (100%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a cytokine belonging to the tumor necrosis factor (TNF) ligand family. It is abundantly expressed in endothelial cells but not in B or T cells. Expression is inducible by TNF and IL-1 alpha. This cytokine binds to receptors TNFRSF25 and TNFRSF21/DR6, activates NF-kappaB and MAP kinases, and induces apoptosis in endothelial cells. It also inhibits endothelial cell proliferation and may act as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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