Thermo Fisher Scientific Emerin Polyclonal Antibody
Thermo Fisher Scientific의 Emerin 폴리클로날 항체는 인간 Emerin 단백질을 표적으로 하는 Rabbit IgG 기반 항체입니다. Western blot 및 면역침강(IP)에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
- 카탈로그번호
- PA517188
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Emerin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunoprecipitation (IP) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding Leu12 of human Emerin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981688 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Xeroderma pigmentosum type G (XPG) is a human genetic disease exhibiting extreme sensitivity to sunlight. The XPG protein, a member of the flap endonuclease 1 (FEN-1) structure-specific DNA repair endonuclease family, is essential for DNA repair of ultraviolet (UV)-induced damages. Human XPG nuclease makes the 3′ incision during nucleotide excision repair of DNA and cleaves model DNA bubble structures near the junction of unpaired and duplex DNA. A 29-amino acid region of human XPG (residues 981–1009) contains PCNA binding activity, with Arg992 being crucial for this interaction. Replication Protein A (RPA) binds specifically to two excision repair proteins: XPA and XPG.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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