
Thermo Fisher Scientific Complement C5 Polyclonal Antibody
인간 Complement C5 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태입니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Thermo Fisher Scientific Complement C5 Polyclonal Antibody
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:3,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1223–1451 of C5 (Uniprot ID# P01031) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11152271 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. It consists of alpha and beta polypeptide chains linked by a disulfide bridge. The activation peptide C5a, an anaphylatoxin with strong spasmogenic and chemotactic activity, is derived from the alpha chain. The C5b cleavage product forms a complex with C6, initiating formation of the membrane attack complex. Mutations cause complement component 5 deficiency, linked to recurrent infections, liver fibrosis, and rheumatoid arthritis.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information: www.P65Warnings.ca.gov
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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