Thermo Fisher Scientific GPR17 Polyclonal Antibody
Human GPR17 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(Paraffin)에서 2 µg/mL로 검증됨. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 단기 4°C·장기 -20°C 보관. 연구용으로 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested at 2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from N-terminal extracellular domain of human GPR17 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2113984 |
Product Specific Information
PA1-32553 detects GPCR GPR17 from human samples.
Target Information
The G-protein-coupled receptor (GPCR) superfamily is comprised of an estimated 600–1,000 members and represents the largest known class of molecular targets with proven therapeutic value.
GPR17 is an orphan G protein-coupled receptor involved in the orchestration of oligodendrocyte differentiation and myelination in the central nervous system.
It is expressed in brain, kidney, heart, and umbilical vein endothelial cells.
GPR17 has dual specificity for uracil nucleotides and cysteinyl leukotrienes and signals through G(i) with inhibition of adenylyl cyclase.
It may mediate brain damage by nucleotides and cysteinyl leukotrienes following ischemia.
Usage Notes
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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