Thermo Fisher Scientific Aurora B Polyclonal Antibody
Aurora B 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체입니다. IHC, ICC/IF 등 다양한 응용에 적합하며, 인간 및 유인원 종에 반응합니다. 항원 친화 크로마토그래피로 정제된 액상 제품으로, 4°C에서 보관합니다.
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Thermo Fisher Scientific Aurora B Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (IHC) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 300 and the C-terminus (residue 344) of human Aurora B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee, and Crab-eating macaque
Target Information
Aurora kinases associate with microtubules during chromosome movement and segregation.
AURKB (Aurora B) localizes to microtubules near kinetochores, specifically to K-fibers.
This complex functions in chromosome alignment and separation, histone modification, and cytokinesis.
The Chromosomal Passenger Complex (CPC) includes INCENP, survivin, and borealin, which regulate activity, localization, and substrate specificity of Aurora B.
AurB is overexpressed in several tumors, including breast and colon cancers, and may interact with Aurora-A kinase through a feedback mechanism.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
제품 이미지
(이미지 파일: IHC-00003_Aurora_B_Q96GD4-1_Rabbit.svg, IHC-00003_Aurora_B_Q96GD4-1_Rabbit_PDP.jpeg)
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