Thermo Fisher Scientific IFITM3 Polyclonal Antibody, FITC
FITC로 표지된 IFITM3 폴리클로날 항체로, 인간 시료에 반응합니다. Western blot, IHC, ELISA, IP 등 다양한 응용에 적합하며, 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 암소 보관이 권장됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1–50 of human Interferon-induced transmembrane protein 3 (IFITM3) |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) containing 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IFITM3 (Interferon Induced Transmembrane Protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein belonging to the interferon-inducible transmembrane (IFITM) family.
These proteins are induced by type I and II interferons and contain multiple interferon-stimulated response elements (ISREs) in their promoter regions.
They play important roles in cellular anti-proliferative activities and homotypic cell adhesion, and are often upregulated in various cancer cells, suggesting a potential role in carcinogenesis.
IFITM3 localizes to the membrane and consists of 133 amino acids. Its expression is induced by IFN-α and IFN-γ and regulated by TEF-1, Brg-1, and Sp1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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