Thermo Fisher Scientific NMDAR2C (extracellular) Polyclonal Antibody
Rabbit polyclonal antibody targeting extracellular region of NMDAR2C. Validated for WB, IHC, and ICC/IF. Lyophilized form, reconstituted with deionized water. Suitable for research use in neuronal and CNS studies.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (IHC) | 1:200 |
| Immunocytochemistry (ICC/IF) | Assay-Dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)RHRLWEMVGRWDH, corresponding to amino acid residues 365–377 of rat NMDAR2C |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2736236 |
Product Specific Information
This antibody is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: Add 50 µL of deionized water.
Target Information
The NMDA Receptor (NMDAR) plays an essential role in memory and neuronal development. It is implicated in several central nervous system disorders, including Alzheimer's disease, epilepsy, and ischemic neuronal cell death. NMDAR is also a principal molecular target for alcohol in the CNS and is potentiated by protein phosphorylation. The NR1 protein can form NMDA-activated channels when expressed in Xenopus oocytes, though these currents are smaller than those observed in situ. More physiological channels are produced when the NR1 subunit combines with one or more NMDAR2 (NR2 A–D) subunits.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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