Thermo Fisher Scientific mGluR7 (extracellular) Polyclonal Antibody
mGluR7 단백질의 세포외 영역을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. Lyophilized 형태로 공급되며 -20°C 보관. 신경전달 관련 연구에 적합한 고품질 시약.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:200 | - |
| Immunohistochemistry (IHC) | Assay-Dependent | - |
| Immunocytochemistry (ICC/IF) | 1:200 | - |
| Flow Cytometry (Flow) | 1:200 | 1 Publication |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide TISGSKKEDTDRKC, corresponding to amino acid residues 377–390 of rat mGluR7 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2736149 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors.
Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in neuropathologic conditions.
Metabotropic glutamate receptors are G protein-coupled receptors divided into three groups based on sequence homology, signal transduction mechanisms, and pharmacologic properties:
- Group I: GRM1, GRM5 (activate phospholipase C)
- Group II: GRM2, GRM3
- Group III: GRM4, GRM6, GRM7, GRM8
Groups II and III are linked to inhibition of the cyclic AMP cascade but differ in agonist selectivity.
Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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(이미지 파일: PA5-77422_mGluR7_P35400-1_Rabbit.svg, PA5-77422_mGluR7_P35400-1_Rabbit_PDP.jpeg)
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