Thermo Fisher Scientific RAD51 Monoclonal Antibody (51RAD01 (3C10))
RAD51 단백질을 타겟하는 Thermo Fisher Scientific의 단일클론 항체로, 인간·마우스·랫트 시료에 반응. Western blot, IHC, ICC/IF, IP 등 다양한 응용 가능. 단백질 G로 정제된 액상 형태로 안정적이며, PBS 버퍼에 보존.
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Thermo Fisher Scientific RAD51 Monoclonal Antibody (51RAD01 (3C10))
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | View 8 publications |
| Immunohistochemistry (IHC) | – | View 6 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–4 µg/mL | View publications |
| Immunocytochemistry (ICC/IF) | 1:10–1:100 | View 13 publications |
| Immunoprecipitation (IP) | 2 µg/mL | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Algae, Human, Mouse, Pig, Protozoa, Yeast |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 51RAD01 (3C10) |
| Immunogen | Recombinant Rad51 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10985045 |
Product Specific Information
MA5-14419 targets RAD51 in IHC (P), IP, ICC/IF, and WB applications and shows reactivity with human, mouse, and rat samples.
The MA5-14419 immunogen is recombinant Rad51 protein.
Target Information
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recombination. It binds to single- and double-stranded DNA and exhibits DNA-dependent ATPase activity.
RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template.
It binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments essential for homology search and strand exchange.
Mutations in the RAD51 gene can result in breast cancer, mirror movements 2, and Fanconi anemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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