Thermo Fisher Scientific USP12 Monoclonal Antibody (OTI1E3), TrueMAB
USP12 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot에서 검증됨. Human 시료에 반응하며, Lyophilized 형태로 제공. PBS 버퍼(8% 트레할로스 포함)에 보관하며, -20°C에서 저장 권장. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1E3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 61–251 of human USP12 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
USP12 is a deubiquitinating enzyme with minimal activity alone; it requires interaction with WDR20 and WDR48 for high activity (PubMed:19075014, PubMed:27373336).
It is not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).
In complex with WDR48, USP12 may act as a tumor suppressor by stabilizing PHLPP1 (PubMed:24145035). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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