
Thermo Fisher Scientific BIRC3 Monoclonal Antibody (OTI1D12), TrueMAB
인간 BIRC3 단백질에 특이적인 단클론 항체로 Western blot 및 Immunocytochemistry에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 아포토시스 억제 단백질 연구에 유용합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 255–529 of human BIRC3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The BIRC3 gene encodes a member of the inhibitor of apoptosis (IAP) protein family.
This protein binds to TRAF1 and TRAF2, likely interfering with activation of ICE-like proteases, thereby inhibiting apoptosis induced by serum deprivation.
It contains three baculovirus IAP repeat domains and a RING finger domain.
Transcript variants encoding the same isoform have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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