Thermo Fisher Scientific USP12 Monoclonal Antibody (OTI2A6), TrueMAB
USP12 단백질을 인식하는 마우스 단클론 항체로 Western blot에 최적화됨. 인간 유래 단백질(aa 61-251)을 면역원으로 제작. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도로 사용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 61–251 of human USP12 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
USP12 is a deubiquitinating enzyme with minimal intrinsic activity, requiring interaction with WDR20 and WDR48 for full activation (PubMed:19075014, PubMed:27373336).
Not involved in the deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014).
In complex with WDR48, it may function as a tumor suppressor by stabilizing PHLPP1 (PubMed:24145035).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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