Thermo Fisher Scientific SIRT6 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

2 µg/mL

-

Immunocytochemistry (ICC/IF)

1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide between amino acids 300-355 of the human SIRT6 protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SIRT6,uniProtId:Q8N6T7-1,ncbiNodeId:9606,antigenRange:300-355,antigenLength:355,antigenImageFileName:PA1-16957_SIRT6_Q8N6T7-1_Rabbit.svg,antigenImageFileNamePDP:PA1-16957_SIRT6_Q8N6T7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

tris citrate/phosphate, pH 7-8

Contains

0.1% sodium azide

Storage conditions

4° C, do not freeze

Shipping conditions

Wet ice

RRID

AB_2188919

Product Specific Information

PA1-16957 is specific for the ~39 kDa SIRT6 protein.

A higher molecular weight band at ~59 kDa may be seen with lower dilutions such as 2 µg/mL.

Suggested positive control: antigen standard for SIRT6 (transient overexpression lysate), Hela whole cell extract.

Target Information

Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.