Thermo Fisher Scientific alpha-1b Adrenergic Receptor Monoclonal Antibody (471802)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

0.25 µg per million cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

471802

Immunogen

NS0 mouse myeloma cell line transfected with human ADRA1B Met1-Phe520 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:alpha-1b Adrenergic Receptor,uniProtId:P35368-1,ncbiNodeId:9606,antigenRange:1-520,antigenLength:520,antigenImageFileName:MA5-24191_alpha-1b_Adrenergic_Receptor_P35368-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24191_alpha-1b_Adrenergic_Receptor_P35368-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608910

Product Specific Information

This antibody stains human ADRA1B transfectants but not irrelevant transfectants.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

The alpha-1b adrenoceptor is an Adrenergic Receptor that causes contraction of smooth muscle cells and thereby controls vascular tone, blood pressure, and accelerates the development of atherosclerosis. Decreased alpha-1b adrenoceptor is associated with benign prostatic hyperplasia (BPH). This adrenergic receptor also acts as a proto-oncogene when transfected into cell lines where constitutive activation of the receptor induces neoplastic transformation. The alpha-1b adrenoceptor has been documented in adrenal, aorta, blood, various brain regions, eye, heart, kidney, liver, prostate, spinal cord, and spleen. ESTs have been isolated from kidney (normal and cancer) and lung carcinoma libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.