Thermo Fisher Scientific Phospho-c-Fos (Ser32) Polyclonal Antibody
인간, 마우스, 랫트 시료에 반응하는 Rabbit Polyclonal 항체로, c-Fos의 Ser32 인산화 부위를 인식합니다. Western blot 및 ELISA에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 완충액에 보관되며 -20°C에서 안정합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:5,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human c-Fos around the phosphorylation site of Ser32 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2609822 |
Product Specific Information
This antibody is predicted to react with mouse and rat based on sequence homology.
Target Information
FBJ murine osteosarcoma viral oncogene homolog, commonly known as Cellular proto-oncogene Fos (c-Fos), belongs to the Fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14.
c-Fos forms a heterodimer with c-Jun to create the Activator Protein-1 (AP-1) transcription factor, which regulates genes involved in cellular signal transduction, proliferation, and differentiation.
It is phosphorylated by various stimuli including growth factors and insulin at multiple sites. The ERK MAPK kinase is a known upstream regulator of phosphorylation at Threonine 232, which controls nuclear localization and transcriptional activity of c-Fos.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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