Thermo Fisher Scientific Mosunetuzumab Recombinant Rabbit Monoclonal Antibody (4G6), MonoRab

Applications and Tested Dilution

• Application: ELISA
• Tested Dilution: 0.01–1 µg/mL

Product Specifications

Product Specific Information

• Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
• Recommended dilutions:
  • Sandwich ELISA: 0.4–2 µg/mL
  • Competitive ELISA: 1–10 µg/mL
• The lyophilized product remains stable up to 1 year at -20°C from date of receipt.
• Upon reconstitution, store for 2–3 weeks at 2–8°C or up to 12 months at -20°C or below.
• Avoid repeated freezing and thawing cycles.

Target Information

Mosunetuzumab is an investigational, humanized, T-cell bispecific antibody designed to engage T cells and redirect their cytotoxic activity against malignant B cells. It binds simultaneously to CD3 epsilon (CD3ε), a component of the T-cell receptor complex, and to CD20, a B-cell surface protein expressed in most B-cell malignancies. This dual binding induces T-cell activation and B-cell killing through crosslinking of the TCR complex.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.