Thermo Fisher Scientific Mosunetuzumab Recombinant Rabbit Monoclonal Antibody (10D5), MonoRab

Applications

• ELISA (ELISA): 0.01–1 µg/mL

Product Specifications

Product Specific Information

• Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL.
• Recommended dilution for sandwich ELISA: 0.5–2 µg/mL
• Lyophilized product remains stable up to 1 year at -20°C from date of receipt.
• After reconstitution: store for 2–3 weeks at 2–8°C or up to 12 months at -20°C or below.
• Avoid repeated freeze/thaw cycles.

Target Information

Mosunetuzumab is an investigational, humanized, T-cell bispecific antibody designed to engage T cells and redirect their cytotoxic activity against malignant B cells. It simultaneously binds to CD3 epsilon (CD3ε), a component of the T-cell receptor (TCR) complex, and to CD20, a B-cell surface protein expressed in most B-cell malignancies. This dual binding crosslinks the TCR, inducing signaling events that lead to B-cell killing.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.