Thermo Fisher Scientific TIRAP Polyclonal Antibody
TIRAP 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체로, Human 시료에 반응합니다. Western blot 및 Immunoprecipitation에 사용 가능하며, 고순도 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific TIRAP Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
- View 2 publications
Immunoprecipitation (IP)
- Tested Dilution: —
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QTLLKKPKKRPNSPE) corresponding to internal amino acids of TIRAP (aa 27–42) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10979679 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
Toll-like receptors (TLRs) are signaling molecules that recognize microbial products during infection and link innate and adaptive immune responses. These proteins act through adaptor molecules such as TIRAP and MyD88 to activate kinases and transcription factors. In TIRAP-deficient mice, TLR signaling via TLR2 ligands (using TLR1 and TLR6 co-receptors) is abolished, indicating that MyD88 and TIRAP are both required for TLR2 signaling. These mice are resistant to LPS toxicity and show defects in NF-κB and MAP kinase activation, suggesting TIRAP involvement in TLR4 signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.