Thermo Fisher Scientific Phospho-STAT2 (Tyr690) Polyclonal Antibody
Phospho-STAT2 (Tyr690)에 특이적인 Rabbit Polyclonal Antibody로 Western Blot에 최적화됨. 인간, 소, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 액상 형태. -20°C 보관, 연구용 전용.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide corresponding to residues surrounding pTyr690 of human Stat2 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10986971 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
STAT2 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by receptor-associated kinases and form homo- or heterodimers that translocate to the nucleus to act as transcription activators.
Upon interferon (IFN) stimulation, STAT2 forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), acting as a transactivator but lacking direct DNA-binding ability. Transcription adaptor P300/CBP (EP300/CREBBP) interacts specifically with STAT2 and may play a role in blocking IFN-alpha response by adenovirus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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