Thermo Fisher Scientific MAP2 Polyclonal Antibody
MAP2 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 사용 가능. 인간, 마우스, 랫 등 반응성. 항원 친화 크로마토그래피로 정제되었으며, 신경세포 연구 및 신경발생 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 4 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 | View 13 publications |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Hamster, Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to carboxy-terminal residues of human MAP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 73.6 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_11006358 |
Product Specific Information
- It is not recommended to aliquot this antibody.
- PA5-17646 was successfully used to detect MAP2 in neurons differentiated from H9 ESC-derived NSCs.
- This antibody is not cross-reactive with tau.
Target Information
MAP2 (Microtubule Associated Protein 2) exists in two high molecular weight forms (MAP2a & MAP2b) and a low molecular weight form. The expression of MAP2 is developmentally regulated and its multiple forms arise by alternative splicing of a single gene. MAP2 is involved in microtubule assembly, an essential step in neurogenesis.
The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins enriched in dendrites, contributing to dendritic shape determination and stabilization during neuron development.
MAP2 is useful in studies of neuron structure in normal and malignant brain tissue as well as in degenerative diseases such as Alzheimer’s Disease (AD).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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