Thermo Fisher Scientific CXCR1 Polyclonal Antibody
CXCR1 단백질을 표적으로 하는 Thermo Fisher Scientific의 폴리클로날 항체입니다. 인간 시료에 반응하며 IHC(파라핀) 실험에 적합합니다. 단백질 가공 시 Proteinase K 항원 회복 권장. 고순도 항원 친화 크로마토그래피로 정제된 액상 형태의 항체입니다.
- 카탈로그번호
- PA533453
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 10–15 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from internal region of human CXCR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550833 |
Product Specific Information
- In IHC applications, antigen retrieval using Proteinase K treatment is recommended.
- Percent identity with other species by BLAST analysis:
- Human, Chimpanzee (100%)
- Gorilla, Orangutan, Gibbon (95%)
- Monkey (90%)
- Marmoset, Elephant (80%)
Target Information
CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8), binding IL8 with high affinity and transducing signals through a G-protein activated second messenger system. Knockout studies in mice suggest that CXCR1 inhibits embryonic oligodendrocyte precursor migration in the developing spinal cord.
The gene IL8RB, encoding another high-affinity IL8 receptor, and IL8RBP, a pseudogene of IL8RB, form a gene cluster mapped to chromosome 2q33–q36.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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