Thermo Fisher Scientific Urokinase Polyclonal Antibody
Thermo Fisher Scientific의 Urokinase Polyclonal Antibody는 Rat, Human, Mouse에 반응하는 Rabbit IgG 항체입니다. IHC(P) 실험에 적합하며, 고순도(>95%) 항원 친화 크로마토그래피로 정제되었습니다. PBS/glycerol 버퍼에 저장되며 연구용으로 사용됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat, Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 211–260 of Human uPA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803331 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer’s disease and decreased affinity for fibrin-binding.
This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative (HMW-uPA) connected by a disulfide bond. HMW-uPA can be further processed into LMW-uPA, which remains proteolytically active but does not bind to the uPA receptor.
Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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