Thermo Fisher Scientific TK1 Monoclonal Antibody (3B3.E11)
인간 TK1 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 ELISA에 적합. 고순도 Protein G 정제, 액상 형태로 제공. 연구용으로만 사용하며 세포 분열 관련 단백질 분석에 유용.
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Thermo Fisher Scientific TK1 Monoclonal Antibody (3B3.E11)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 10 µg/mL |
| ELISA | 2–5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B3.E11 |
| Immunogen | His-tagged recombinant human thymidine kinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.09 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2203437 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Thymidine Kinase (TK1) is a highly conserved phosphotransferase present in most living cells. It catalyzes the phosphorylation reaction:
deoxythymidine + ATP → deoxythymidine 5′-phosphate + ADP.
This enzyme is involved in introducing deoxythymidine into DNA and is required for the action of many antiviral drugs such as azidothymidine (AZT). TK1 is also used to select hybridoma cell lines in monoclonal antibody production. Clinically, TK1 serves as a marker of cell division activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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